Mahindra current affairs magazine
Mahindra current affairs magazine Published this article page no 108 MAPPING THE INDIAN GENOME Why in news? Union government has given clearance to an ambitious gene mapping project known as the Genome India Project with an estimated worth of Rs 238 crores. More on the news The project has been cleared by Department of Biotechnology (under the Ministry of Science and Technology). It involves 20 leading institutions including the Indian Institute of Science in Bengaluru and a few IITs. The Centre for Brain Research an autonomous institute of IISc Bengaluru will serve as the nodal point of the project. 68 The first stage of the project will look at samples of 10000 persons from all over the country to form a grid that will enable the development of a Reference Genome. About Genome mappingsequencing A genome is the entire DNA or sequence of genes in a cell. Simply put the genome is divided into chromosomes chromosomes contain genes and genes are made of DNA. Each genome has approximately 3.2 billion DNA base pairs. Sequencing a genome means deciphering the exact order of base pairs in an individual. The way these base pairs are arranged or variations and mutations in their pattern can provide clues about the individuals health or ill health inherited or acquired. Significance of the project Existing global genetic studies of the Human Genome Project are based mainly on Caucasian urban middle class samples (95%) which are not considered representative of all humans. This project holds importance to ensure that India with its unparalleled human diversity both horizontal (caused by migration and intermixing of races) and vertical (caused due to endogamy resulting in specific patterns of trait inheritance) is adequately represented in terms of genomic data download download mahendra current affairs magazine.

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